Erectile dysfunction · Up to 36 hours
Tadalafil tablets for erectile dysfunction
Tadalafil is a prescription-only tablet for erectile dysfunction, and the same active ingredient as Cialis. One dose can work for up to 36 hours, so there's less need to plan around a time.3
From £12.98 a month
Check your eligibility →- CQC registered
- UK-registered clinicians
- Plain, discreet delivery

All content on this page has been medically reviewed by Naeem Teni, Clinical Lead. GPhC 2215591.
Pricing
Pick a strength, pick a pack.
Your clinician sets the strength. The bigger the pack, the less each one costs.
10mg
20mg
How it works
What it does in the body.

Blood flow, not desire
An erection depends on blood flowing into the penis. Tadalafil helps the blood vessels there relax, so more blood can reach where it's needed.3
It blocks an enzyme called PDE5
PDE5 breaks down the messenger that keeps those vessels open during arousal. Tadalafil slows it, so the effect holds.3
Why it lasts longer
Tadalafil stays in your body much longer than sildenafil, which is where the 36-hour window comes from.3
Arousal still has to happen
It won't cause an erection on its own. You still need to be sexually stimulated.

Drinking? A lot of alcohol makes erections harder to get, with or without treatment.
Is it right for me?
Who it suits, and what to expect.
May be considered if
All of these usually apply
- You're an adult (18 or over) living in the UK.
- You've had trouble getting or keeping an erection often enough that it's bothering you, rather than the odd off night.
- You're happy for a clinician to look at what might be causing it, not just treat the symptom.
- A clinician judges it safe with your health history and anything else you take.
Not suitable if
Any one of these rules it out
- You take nitrates (for chest pain or heart conditions), the combination can be dangerous.
- You have certain heart or blood-pressure conditions a clinician will ask about.
- You're allergic to tadalafil or any of its ingredients.
- A clinician decides the possible side effects or risks outweigh the benefit.
Not sure where you fit? You don't need to work it out yourself. The assessment asks the right questions, and a clinician checks your answers.
Most side effects are mild and ease with time.3
More common
Usually mild, and often short-lived.
Get help straight away if
These are rare, but need a doctor quickly.
- An erection lasting more than 4 hours. This needs urgent treatment to avoid lasting damage.
- Sudden loss of vision in one or both eyes.
- Sudden loss or reduction of hearing, sometimes with ringing or dizziness.
- Chest pain during or after sex. Stop, sit up, and don't use a nitrate spray.
Never with nitrates or poppers. Taking tadalafil with nitrates (for chest pain) or poppers can drop your blood pressure dangerously.3
Sildenafil or tadalafil?
Tadalafil or sildenafil?
Trial figures come from different studies in different men, so they aren't a direct ranking. Your clinician will talk through which suits your routine.
Common questions
Sildenafil, answered.
Is Manova a proper clinic, or a website?
Will it turn up in a branded box at my office?
What if the clinician says no?
Am I locked into a contract?
How is this different from going to my GP?
Guides
Read up on Tadalafil.
References (4)
- Brock GB, et al. Efficacy and tolerability of tadalafil in men with erectile dysfunction. J Urol. 2002;168:1332–1336.
- Porst H, et al. Tadalafil allows men with erectile dysfunction to have successful intercourse up to 36 hours postdose. Urology. 2003;62(1):121–125.
- Cialis (tadalafil) Summary of Product Characteristics. Electronic Medicines Compendium (EMC).
- Viagra (sildenafil) European Public Assessment Report, scientific discussion. European Medicines Agency.

