Key takeaways
- In 2025 the MHRA seized illegal medicines worth almost £45m, including 5,680 falsified or illegal GLP-1 weight loss pens.
- Any seller offering these medicines without a prescription is breaking the law, whatever their website looks like.
- You can check a UK pharmacy on the General Pharmaceutical Council register — its registration number should be displayed on the site.
- Retatrutide and other unlicensed products are being sold online in the UK. Unlicensed means no regulator has assessed them.
Demand for weight-management medicines has created a criminal market alongside the legitimate one, and it is not small. In 2025 the MHRA seized illegal medicines worth almost £45 million, including 5,680 falsified or illegal GLP-1 weight-loss pens, and dismantled an illicit manufacturing facility in Northampton [1].
This page explains how to tell the difference. It is information, not advice about treatment.
The rule that does most of the work
These are prescription-only medicines. Any seller who will supply one without a prescription is breaking the law — and if they are willing to break that law, the question of what is actually in the pen becomes an open one.
The MHRA’s own phrasing, from its July 2026 campaign, is direct: if you are offered GLP-1 medicines “without the need for a prescription — walk away” [2].

How to check who you are buying from
1. Check the GPhC register. Any legitimate UK online pharmacy is registered with the General Pharmaceutical Council and should display its registration number, usually in the footer or on an “about us” page. You can look that number up on the GPhC register [4]. If there is no number, that is the end of the conversation.
2. Expect a real consultation. A proper service asks about your medical history, your other medicines, pregnancy plans, and your height and weight in a way it can verify. It must be able to say no. A form that approves everyone is not a safety process.
3. Expect a named prescriber. You should be able to find out who is responsible for the prescribing decision.
4. Be suspicious of the sales pitch. Prescription-only medicines cannot legally be advertised to the public. In June 2026 the MHRA, ASA and GPhC jointly warned that naming these medicines, or using phrases like “GLP-1 tablets” or “the new weight-loss tablets” in advertising — including advertising waiting lists — is likely to breach the advertising code [6]. A company promoting a named prescription medicine at you is telling you something about itself.
The warning signs
- No prescription needed, or a “consultation” that is a single tick-box
- Sold through social media, a beauty salon, a gym or a private message
- No GPhC registration number anywhere on the site
- Prices far below everyone else
- Products named that are not licensed in the UK
- No patient information leaflet, or one in another language
- Payment by bank transfer or cryptocurrency only
Unlicensed is not the same as unavailable
Some products sold online are not counterfeits of licensed medicines — they are experimental compounds that no regulator has approved. The MHRA specifically named retatrutide in July 2026 as an example of an unlicensed product being sold illegally in the UK [2].
Retatrutide is a genuine investigational medicine in phase 3 trials, with published results that look promising. It is also not licensed anywhere in the world, which means no regulator has assessed its manufacture, its dosing or its long-term safety, and nothing sold under that name online has been checked by anyone. The same applies to any product marketed as “research use only” or sold in a vial for you to draw up yourself.
It has already reached UK patients
In February 2026 the MHRA issued an alert about falsified Mounjaro KwikPens from batch D873576, supplied through a clinic in Birmingham. Five affected pens were identified. Testing found tirzepatide was present, but the dose mechanism failed and sterility could not be assured [3].
Sterility matters: an unsterile injection puts material directly under the skin, bypassing every barrier your body has.
If you think you have a fake
- Stop using it.
- Keep the packaging and batch number.
- Report it through the Yellow Card scheme, which takes reports about falsified medicines as well as side effects [7], and report the seller to the MHRA [5].
- Seek medical advice if you feel unwell, and say exactly what you have taken.
The wider point
The reason people buy from these sellers is usually not recklessness. It is cost, or being turned down, or a long wait. Those are real problems, and the honest answer is that a medicine you cannot verify is not a solution to any of them — it is a different risk wearing the same packaging.
If cost or eligibility is the barrier, that is worth discussing with a GP or a registered pharmacy, including what NHS services exist in your area.
Frequently asked questions
How do I know if a weight loss pen is genuine?
Buy only from a pharmacy registered with the General Pharmaceutical Council, after a proper consultation and a prescription. Check the registration number on the GPhC register. Genuine medicines arrive with a patient information leaflet, correct labelling and an intact seal.
Is it illegal to buy weight loss injections without a prescription?
These are prescription-only medicines. Supplying them without a prescription is illegal, and the MHRA's advice is blunt: if you are offered GLP-1 medicines without needing a prescription, walk away.
What is retatrutide and can I buy it?
Retatrutide is an experimental medicine still in phase 3 trials. It is not licensed anywhere. The MHRA named it in July 2026 as an example of an unlicensed product being sold illegally online. Nothing sold under that name has been assessed by any regulator.
Have counterfeit pens actually reached patients in the UK?
Yes. In February 2026 the MHRA issued an alert about falsified Mounjaro KwikPens from one batch supplied through a Birmingham clinic. The pens contained tirzepatide but sterility could not be assured and the dose mechanism failed.
What should I do if I think I have bought a fake?
Stop using it, keep the packaging, and report it to the MHRA through the Yellow Card scheme. If you feel unwell, seek medical advice and say what you have taken.
References
- MHRA. MHRA seizes illegal medicines worth almost £45m in 2025, disrupting major criminal networks. 26 January 2026. www.gov.uk/government/news/mhra-seizes-illegal-medicines-worth-almost-
- MHRA. No summer shortcut for safe weight loss. 24 July 2026. www.gov.uk/government/news/no-summer-shortcut-for-safe-weight-loss
- MHRA. Falsified Mounjaro (tirzepatide) KwikPen: Drug Safety Update, 24 February 2026. assets.publishing.service.gov.uk/media/699da78e532c9ad91ebbcbe3/Falsif
- General Pharmaceutical Council. Check the registration of an online health service. www.pharmacyregulation.org/patients-and-public/standards-you-can-expec
- MHRA. Report an unlicensed or suspicious online medicine seller. medicine-seller-register.mhra.gov.uk/report
- MHRA, ASA and GPhC. Warning on promoting newly licensed prescription only medicines and unlicensed medicines for weight management. 18 June 2026. www.gov.uk/government/news/warning-on-promoting-newly-licensed-prescri
- MHRA. Yellow Card: report a suspected side effect. yellowcard.mhra.gov.uk/
Medical reviewer
Naeem Teni
Clinical Lead at Manova. Registered pharmacist and independent prescriber, GPhC 2215591. Reviews Manova’s clinical content for accuracy and safety.
Written by
Manova Editorial Team
Researched and written to our editorial policy, using NICE, NHS, MHRA and peer-reviewed sources.
This article is for general information and isn’t a substitute for advice from your own clinician. If you feel unwell, contact your GP or NHS 111. In an emergency, call 999.