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Category: Weight loss

Evidence-based articles on weight, written by the Manova editorial team and medically reviewed by our clinical lead. Every article lists the research it is based on.

Hydration and weight loss: what water actually does

Illustration of a glass of water before a meal and a stomach filling

One hydration claim has randomised evidence behind it, one is real but trivial, and one is a number somebody made up in the 1940s. Worth telling them apart.

Weight and asthma: a different kind of asthma, and a diagnosis worth checking

Illustration of lung mechanics and airway inflammation in obesity

Poor asthma control in someone with obesity is often blamed on inhaler technique. Frequently it is neither technique nor adherence — it is a different disease process.

Weight loss and gallstones: why losing weight fast raises the risk

Illustration of the gallbladder and bile ducts with stone formation

The gallbladder is the one organ that does badly out of fast weight loss. Knowing why turns it into something you can largely design around.

Training fasted: does exercising before breakfast burn more fat?

Illustration comparing fat oxidation during exercise with 24-hour fat balance

Fasted cardio is one of the few fitness claims where the mechanism is real and the outcome still is not there. Here is where the gap opens up.

Artificial sweeteners and weight: what the evidence actually shows

Illustration contrasting short-term trial results with long-term cohort findings on sweeteners

The headlines said the WHO had told people to stop using sweeteners. What it issued was a conditional recommendation on low certainty evidence. Those two words did most of the work.

Glycaemic index explained: what it measures, and what it does not

Illustration comparing blood glucose curves after two different carbohydrate foods

A number measured on a lone food eaten by a fasted volunteer, then applied to a plate of dinner. It tells you something — just not most of what it is sold as telling you.

Sarcopenia: why strength matters more than muscle size

Illustration of the three-step sarcopenia assessment from strength to quantity to performance

The definition changed in 2019, and the change tells you something useful: what you can do with the muscle matters more than how much of it there is.

Body recomposition: losing fat and gaining muscle at once

Illustration comparing fat mass and lean mass changing in opposite directions

It is possible, it is slow, and most of the dramatic before-and-after claims are within the error bars of the machine that measured them.

Weight and back pain: a real link, but a modest one

Illustration of the association between body weight and low back pain risk

The association is real and consistent. What it is not is strong, and it is not obviously mechanical either.

Weight and gout: why losing weight can trigger a flare first

Illustration of the pathway from excess body fat to raised serum urate

Losing weight lowers urate in the long run and can raise it sharply in the short run. Knowing which phase you are in changes what you should expect.

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