Weight, testosterone and energy in men
Carrying extra weight lowers testosterone, and losing it raises testosterone back. The direction of that relationship matters more than most men are told.
Storing and travelling with weight loss medicines
Fridge rules, how long a pen survives out of it, what to do at airport security, and where used needles are supposed to go.
Buying weight loss medicines safely: how to spot an illegal seller
The MHRA seized 5,680 illegal weight-loss pens in a single year. Here’s how to check who you are actually buying from.
Who should not take weight loss medicines
The formal contraindication list is shorter than people expect. The list of things that need discussing first is much longer.
GLP-1 medicines beyond weight: heart, kidney and sleep apnoea
Three large trials moved these medicines from weight to organs. What each one measured, and what the UK licence now covers.
Muscle loss on weight loss medicines: what the evidence shows
Roughly a quarter of the weight lost in the tirzepatide body-composition data was lean mass. Here is what that figure does and does not mean.
Weight loss medicines, contraception and pregnancy
There is specific MHRA advice here, and it surprises people — particularly the part about the pill and tirzepatide.
Alcohol and weight loss medicines: what to know
There is no outright prohibition in the product information, and several reasons for caution. Also: the odd finding that these medicines seem to reduce the wish to drink.
Nausea on weight loss medicines: what actually helps
It is the commonest reason people stop, and most of it is manageable. What the product information says, and what actually makes a difference.
Switching between weight loss medicines: what to know
There is no dose conversion chart, because nobody has published one. Here’s what that actually means when a switch is being considered.