Weight loss medicines, contraception and pregnancy

There is specific MHRA advice here, and it surprises people — particularly the part about the pill and tirzepatide.
Alcohol and weight loss medicines: what to know

There is no outright prohibition in the product information, and several reasons for caution. Also: the odd finding that these medicines seem to reduce the wish to drink.
Nausea on weight loss medicines: what actually helps

It is the commonest reason people stop, and most of it is manageable. What the product information says, and what actually makes a difference.
Switching between weight loss medicines: what to know

There is no dose conversion chart, because nobody has published one. Here’s what that actually means when a switch is being considered.
Orlistat: how it works and who it suits

The oldest weight-loss medicine still in wide use, and the only one you can get without a prescription. It works in the gut, not the brain.
Saxenda (liraglutide): where it fits now

The original of the type, now the least fashionable. It is still licensed, still works, and the daily injection is the reason most people move on.
Weight loss injections vs tablets: how the options compare

Four licensed medicines, two delivery methods, and a lot of confusion. A factual comparison of what each one actually is.
Wegovy tablets: the oral version explained

Same medicine, different delivery, and a fairly demanding set of instructions. Here’s what the licence covers and what the trial measured.
Foundayo (orforglipron): the weight loss tablet explained

The UK became the first country in Europe to license it. Here’s what the regulator actually approved, and what the trials behind it measured.
Wegovy 7.2 mg: what the higher dose means

A higher maximum dose of semaglutide was licensed in the UK in 2026. Here’s what the regulator approved and what the trial behind it actually measured.